Are there long-term effects of trypan blue?

In surgery over 90% of the CAPSULBlue is removed by rinsing unabsorbed dye and extraction of the stained capsular disk during surgery. The remaining trypan blue (CAPSULBlue) washes out of the eye naturally within a few hours following surgery.

On a global basis, trypan blue is used in over 10% of cataract surgeries for complex cataract cases and training.  Trypan blue has a great safety profile as reported in the peer-review literature and the FDA MAUDE database.